反应详情

温度

70 °C

To the residue of α-sodioformyl-β-formylaminopropionitrile is added 300 parts by volume of tetrahydrofuran and 138 parts of dimethyl sulfate. The mixture is reacted under stirring at 70°C for 5 hours. After completion of the reaction, the mixture is cooled at 25°C. The precipitated sodium methyl sulfate is removed and the filtrate is concentrated and kept standing overnight, whereby 135 parts of α-methoxymethylene-β-formylaminopropionitrile is obtained as crystals.

1. customThe mixture is reacted
2. customAfter completion of the reaction
3. temperaturethe mixture is cooled at 25°C
4. customThe precipitated sodium methyl sulfate is removed
5. concentrationthe filtrate is concentrated
6. waitkept standing overnight