3-Aminopropionitrile → HCID 178511136, compound

HRID 1075783Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][C:4]#[N:5].C([O:8][CH2:9]C)=O.[C]=O.[CH3:13][O-:14].[Na+:15]>>[Na:15][C:13]([CH:3]([CH2:2][NH:1][CH:9]=[O:8])[C:4]#[N:5])=[O:14]

Participants

Reactant 4

HCID 16473-Aminopropionitrile

HCID 8025Ethyl formate

HCID 10942334Sodium Methoxide

HCID 178418416HCID 178418416, compound

Product 1

HCID 178511136HCID 178511136, compound

Procedure

A method according to claim 1 in which in said step (a) β-amino-propionitrile is reacted with ethyl formate and carbon monoxide in the presence of sodium methylate at a temperature of 70°C to obtain α-sodioformyl-β-formylamino propionitrile.

Sources & evidence

ORD record: ord-0f7d7834e1784eacabb9be9ecf677ba8
Source dataset: uspto-grants-1976_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03954756

Reaction notes

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