Iodine → HCID 12934766, compound

Participants

Reaction Steps

A mixture of 2.8 g 7-azaindole in 25 ml methanol and 3.5 g 1,4,5,6-tetrahydro-2-pyrimidinethiol in 50 ml methanol is added to a well-stirred solution of 7.6 g iodine and 15 g potassium iodide in 50 ml water. The mixture is stirred at room temperature for 14 hours and filtered. The precipitate is washed with water and ether and then recrystallised from water to give 3-(1,4,5,6-tetrahydro-2-pyrimidinylthio)-7-aza-indole hydriodide melting at 294°-295°.

Provenance & Evidence