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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1075809Generated: October 31, 2026

Hydrochloric Acid → 5-Fluorouracil

https://huagongshe.com/reaction/1075809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 12829550HCID 12829550—
Product5-FluorouracilHCID 338574.9%

Reaction Steps

0.41 g of 5-fluoro-6-isopropoxy-5,6-dihydrouracil was placed in a reflux flask and then 1 ml of concentrated HCl was added to the flask. Precipitation of a solid occurred a few minutes after reaching reflux conditions, yielding 0.21 g of 5-fluorouracil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03954759
Source datasetuspto-grants-1976_05
ORD IDord-9116ae8a2fa44260b8762b0867af63b3
Source noteuspto-grants-1976_05