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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1075810Generated: November 1, 2026

2,4(1H,3H)-Pyrimidinedione, 5-fluorodihydro-6-hydroxy- → 5-Fluorouracil

https://huagongshe.com/reaction/1075810

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4(1H,3H)-Pyrimidinedione, 5-fluorodihydro-6-hydroxy-HCID 3650—
ReactantHCID 12829550HCID 12829550—
Product5-FluorouracilHCID 3385—

Reaction Steps

Example 15 was repeated, using 5-fluoro-6-hydroxy-5,6-dihydrouracil obtained in Example 5 for the 5-fluoro-6-isopropoxy-5,6-dihydrouracil. 5-fluorouracil was obtained as the product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03954759
Source datasetuspto-grants-1976_05
ORD IDord-739bf73c10454cbc87fc37f11ce62ef5
Source noteuspto-grants-1976_05