HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 10,11-Dihydro-3-methoxy-8-(methylthio)-dibenzo thiepin-10-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 3-methoxy-8-methylthio-dibenzo[b,f]thiepin-10(11H)-one | HCID 12822195 | — |
| Solvent | Water | HCID 962 | — |
| Product | 10,11-Dihydro-3-methoxy-8-(methylthio)-dibenzo thiepin-10-ol | HCID 21541197 | — |
Reaction Steps
17.8 G. of 3-methoxy-8-(methylthio)-dibenzo[b,f]thiepin-10(11H)-one is suspended in 150 ml. of ethanol and reacted with 38 g. of sodium borohydride. The reaction mixture is stirred for 90 minutes, and subsequently treated with water and extracted with ether. The organic phase is washed with water, dried over magnesium sulfate and evaporated, whereby there is obtained 10,11-dihydro-3-methoxy-8-(methylthio)-dibenzo[d,f]thiepin-10-ol having a melting point of 122°-124°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03954764 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-bee840270add48898f1237dbb4de0ce9 |
| Source note | uspto-grants-1976_05 |