2-Methylbenzoyl chloride → HCID 20441568, compound

HRID 1075900Notes

Reaction equation

HRID 1075900 reaction equation
C(O)(=O)/C=C\C(O)=O.[Cl:9][C:10]1[N:15]=[N:14][C:13]2[CH2:16][CH2:17][NH:18][CH2:19][C:12]=2[CH:11]=1.[C:20]1([CH3:29])[C:21]([C:26](Cl)=[O:27])=[CH:22][CH:23]=[CH:24][CH:25]=1>C(O)C.CCOCC>[Cl:9][C:10]1[N:15]=[N:14][C:13]2[CH2:16][CH2:17][N:18]([C:26]([C:21]3[C:20]([CH3:29])=[CH:25][CH:24]=[CH:23][CH:22]=3)=[O:27])[CH2:19][C:12]=2[CH:11]=1

Participants

4

Reactant 2

HCID 702762-Methylbenzoyl chlorideHCID 86733381HCID 86733381, compound

Product 1

HCID 20441568HCID 20441568, compound

Reagents, catalysts & solvents 1

HCID 21585056Diethyl ether ethanolSolvent

Procedure

Produced in a manner analogous to that described in Example 8 (g), from 28.5 g of 3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine maleate and 16.9 g of o-toluoyl chloride. Reaction time 24 hours. M.P. 123°-126° (decomp., from 95% ethanol/ether).

Workup

  1. customProduced in a manner analogous to
  2. customReaction time 24 hours

Sources & evidence

ORD record
ord-08ade4c2937a4148a130308c9888bcbe
Source dataset
uspto-grants-1976_05
Patent number
US03954754

Reaction notes

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