Hydrazine hydrate (1:1) → HCID 12582677, compound

HRID 1075914Notes

Reaction equation

HRID 1075914 reaction equation
[CH2:1]([O:3][C:4]1[CH:22]=[CH:21][C:7]([C:8]([N:10]2[CH2:20][CH2:19][C:13]3[N:14]=[N:15][C:16](Cl)=[CH:17][C:12]=3[CH2:11]2)=[O:9])=[CH:6][CH:5]=1)[CH3:2].O.[NH2:24][NH2:25]>>[CH2:1]([O:3][C:4]1[CH:22]=[CH:21][C:7]([C:8]([N:10]2[CH2:20][CH2:19][C:13]3[N:14]=[N:15][C:16]([NH:24][NH2:25])=[CH:17][C:12]=3[CH2:11]2)=[O:9])=[CH:6][CH:5]=1)[CH3:2]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20441597HCID 20441597, compound

Product 1

HCID 12582677HCID 12582677, compound

Procedure

11.1 g of 6-(p-ethoxybenzoyl)-3-chloro-5,6,7,8-tetrahydropyrido[4,3-c]pyridazine and 60 cc of hydrazine hydrate are stirred at a bath temperature of 100° for 1 hour and 40 minutes. The title compound has a M.P. of 171°-173° (decomp., from absolute ethanol).

Workup

  1. custom40 minutes

Sources & evidence

ORD record
ord-2061b7669d9a4c22ae571bfe9f404805
Source dataset
uspto-grants-1976_05
Patent number
US03954754

Reaction notes

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