Hydrazine hydrate (1:1) → HCID 54489213, compound

Participants

Reaction Steps

A solution of 20.3 g of crude oily 3-chloro-5,6,7,8-tetrahydro-6-pyrido[4,3-c]pyridazinecarboxylic acid phenyl ester in 100 cc of hydrazine hydrate is stirred in an oil bath of 100° for 11/2 hours. The reaction solution is concentrated in a vacuum and the residue is divided between 225 cc of chloroform and 25 cc of water. The crude title compound is obtained as semicrystalline residue upon concentrating the organic phase in a vacuum.

Provenance & Evidence