反应详情

To a solution of 0.15 g. of 1-methyl-2-nitro-5-hydroxymethylimidazole in 20 ml. of benzene, 0.33 g. of MnO2 is added and the reaction mixture is heated on the steambath for 2 hours. After filtration and evaporation to dryness under vacuum, the crude product is crystallized from ethyl acetate and 0.060 g. (40.5%) of 1-methyl-2-nitro-5-imidazolaldehyde is obtained.

1. temperaturethe reaction mixture is heated on the steambath for 2 hours
2. filtrationAfter filtration and evaporation to dryness under vacuum
3. customthe crude product is crystallized from ethyl acetate and 0.060 g