HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-2-nitro-1H-imidazole-5-methanol → 1-Methyl-2-nitro-1H-imidazole-5-carboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-2-nitro-1H-imidazole-5-methanol | HCID 70292 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Methyl-2-nitro-1H-imidazole-5-carboxaldehyde | HCID 100390 | 40.5% |
Reaction Steps
To a solution of 0.15 g. of 1-methyl-2-nitro-5-hydroxymethylimidazole in 20 ml. of benzene, 0.33 g. of MnO2 is added and the reaction mixture is heated on the steambath for 2 hours. After filtration and evaporation to dryness under vacuum, the crude product is crystallized from ethyl acetate and 0.060 g. (40.5%) of 1-methyl-2-nitro-5-imidazolaldehyde is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03954789 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-46bcf94c66ce401ebe1aefe460d1fb12 |
| Source note | uspto-grants-1976_05 |