Sodium Chloride → HCID 57234554, compound
Reaction equation
[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([C:12]([OH:14])=[O:13])=[CH:4][CH:3]=1.[Na][Na].[Na].[Cl-].[Na+].[OH-:20].[Na+]>>[Br:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([C:12]([O:14][C:12]([C:5]2[C:6]3[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=3)[C:2]([Br:1])=[CH:3][CH:4]=2)=[O:20])=[O:13])=[CH:4][CH:3]=1Participants
Procedure
When the chlorination reaction is complete, the mixture is worked up according to known methods. After clarification by filtration, where required, the solution may be acidified with a mineral acid at room temperature or at a temperature of up to about 90°C, the bromination product which has precipitated may be separated, washed with water and dried at 100°-120°C. An especially pure product is obtained by salting out the resulting 4-bromo-naphthalic acid in the form of the disodium salt by an addition of sodium ions to the reaction solution, for example in the form of sodium chloride and/or sodium hydroxide, separating the salt and converting it into the anhydride by introducing it into a dilute mineral acid. The 4-bromo-naphthalic acid anhydride so obtained is a valuable intermediate product for the preparation of dyestuffs and optical brighteners of the series of the naphthalic acid derivatives substituted in 4-position by phenols, thiophenols and aromatic amines.
Workup
- customWhen the chlorination reaction
- filtrationAfter clarification by filtration, where
- custommay be acidified with a mineral acid at room temperature or at a temperature
- customup to about 90°C
- customthe bromination product which has precipitated may
- custombe separated
- washwashed with water
- customdried at 100°-120°C
- customAn especially pure product is obtained
- additionby introducing it into a dilute mineral acid
Sources & evidence
- ORD record
- ord-0f692fa85a7f4d6483cff55d2a06fbeb
- Source dataset
- uspto-grants-1976_05
- Patent number
- US03954810
Reaction notes
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