Oxalic Acid → HCID 68136348, compound

HRID 1076090Notes

Reaction equation

HRID 1076090 reaction equation
[CH3:1][C:2]1[C:6]([CH3:7])=[CH:5][S:4][C:3]=1[CH:8]([OH:14])[CH2:9][NH:10][CH:11]([CH3:13])[CH3:12].[C:15]([OH:20])(=[O:19])[C:16]([OH:18])=[O:17]>CCOCC>[C:15]([OH:20])(=[O:19])[C:16]([OH:18])=[O:17].[CH3:1][C:2]1[C:6]([CH3:7])=[CH:5][S:4][C:3]=1[CH:8]([OH:14])[CH2:9][NH:10][CH:11]([CH3:12])[CH3:13]

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 21541773HCID 21541773, compound

Product 1

HCID 68136348HCID 68136348, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To 1.20 g of 1-(3-methyl-4-methylthiophenyl)-2-isopropylaminoethanol in 40 ml of ether, 0.45 g of oxalic acid in 50 ml of ether are dropwise added while stirring. The precipitate is filtered and washed with ether, then crystallised from a methanol-ether mixture. MP (°C): 165.5° - 167.5°.

Workup

  1. filtrationThe precipitate is filtered
  2. washwashed with ether
  3. customcrystallised from a methanol-ether mixture
  4. custom167.5°

Sources & evidence

ORD record
ord-d095d552bc6849c8bed7e3a65e3bf9b6
Source dataset
uspto-grants-1976_05
Patent number
US03954871

Reaction notes

Loading…