Propylene Glycol → HCID 178512755, compound

Participants

Reaction Steps

500 mg of finely pulverized Robenidine HCl was introduced to a previously melted 10 g of polyoxy ethylene triglyceride (Arlatone 289 - Atlas Corp.) The mixture was heated and stirred at 60°-80° until a fine paste was obtained. 66.6 ml of a solution prepared from 75 ml of polyethylene glycol (Carbowax 300) and 25 ml of propylene glycol was added and the mixture was stirred and heated at 60°-80° until a clear solution was obtained. After cooling to room temperature the solution was filtered. The solution had a concentration of 0.65 g of Robenidine HCl. 2.3 ml of said composition in 1 L of water yielded a concentration of 30 mg of Robenidine/ 1 L of water.

Provenance & Evidence