Sodium Bicarbonate → HCID 6604391, compound

HRID 1076160Notes

Reaction equation

HRID 1076160 reaction equation
[CH3:1][C:2]1([CH3:32])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@@H:13]([NH2:20])[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([O:23][CH2:24][O:25][C:26]([C:28]([CH3:31])([CH3:30])[CH3:29])=[O:27])=[O:22].Cl.C(=O)(O)[O-].[Na+]>C(OCC)C>[CH3:1][C:2]1([CH3:32])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@@H:13]([NH2:20])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([O:23][CH2:24][O:25][C:26]([C:28]([CH3:31])([CH3:30])[CH3:29])=[O:27])=[O:22]

Participants

4

Reactant 2

HCID 516892Sodium Bicarbonate2×HCID 76313488HCID 76313488, compound2×

Product 1

HCID 6604391HCID 6604391, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Pivampicillin was prepared in the crystalline state by a balanced addition of aqueous solutions of pivampicillin hydrochloride (solution A) and sodium bicarbonate (solution B) to a stirred 7% aqueous diethyl ether solution (500 ml) at 25° C. keeping the pH in the 6.0 - 6.5 range.

Sources & evidence

ORD record
ord-97040efd80b84dc8834f733bc64ae09b
Source dataset
uspto-grants-1976_05
Patent number
US03956279

Reaction notes

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