Ethanol → HCID 53703774, compound

HRID 1076195Notes

Reaction equation

HRID 1076195 reaction equation
S(=O)(=O)(O)O.[N+:6]([C:9]1[O:22][C:12]([CH:13](CC([O-])=O)CC([O-])=O)=[CH:11][CH:10]=1)([O-:8])=[O:7].C(O)C.[CH3:26][O:27][C:28]1[CH:29]=[C:30]2[C:34](=[CH:35][C:36]=1[O:37][CH3:38])[NH:33][N:32]=[C:31]2[C:39]([NH:41][NH2:42])=[O:40]>CN(C)C=O>[N+:6]([C:9]1[O:22][C:12]([CH:13]=[N:42][NH:41][C:39]([C:31]2[C:30]3[C:34](=[CH:35][C:36]([O:37][CH3:38])=[C:28]([O:27][CH3:26])[CH:29]=3)[NH:33][N:32]=2)=[O:40])=[CH:11][CH:10]=1)([O-:8])=[O:7]

Participants

6

Reactant 4

HCID 702EthanolHCID 1118Sulfuric AcidHCID 69821647HCID 69821647, compoundHCID 70394432HCID 70394432, compound

Product 1

HCID 53703774HCID 53703774, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

5 ml. of concentrated sulfuric acid are added dropwise to the suspension of 6 g. of 5-nitrofurfurylidenediacetate in 100 ml. of ethanol, and the mixture is stirred for 10 to 30 minutes at 50°C. Thereafter a solution of 6 g. of 5,6-dimethoxyindazole-3-carboxylic acid hydrazide in 100 ml. of dimethylformamide is added, and the mixture is allowed to stand at room temperature for 24 hours. 6.3 g. (70 %) of 5,6-dimethoxyindazole-3-carboxylic acid-(5'-nitro-furfurylidene)-hydrazide are obtained; m.p.: 334°C. This compound is identical with Compund 26 of Table 5.

Sources & evidence

ORD record
ord-1c5389c148874dcca7f9bb409836107a
Source dataset
uspto-grants-1976_05
Patent number
US03956312

Reaction notes

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