Aminoacetaldehyde dimethyl acetal → HCID 178495881, compound

HRID 1076204Notes

Reaction equation

HRID 1076204 reaction equation
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]2[NH:6][C:7](=S)[C:8]3[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=3[NH:10][C:4]=2[CH:3]=1.[CH3:18][O:19][CH:20]([O:23][CH3:24])[CH2:21][NH2:22]>C(O)CCC>[CH3:18][O:19][CH:20]([O:23][CH3:24])[CH2:21][NH:22][C:7]1[C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[NH:10][C:4]2[CH:3]=[C:2]([Cl:1])[CH:17]=[CH:16][C:5]=2[N:6]=1

Participants

4

Reactant 2

HCID 89728Aminoacetaldehyde dimethyl acetalHCID 24104717HCID 24104717, compound

Product 1

HCID 178495881HCID 178495881, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

In the manner given in Example 1, 7-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepine-11-thione is treated with aminoacetaldehyde dimethyl acetal in n-butanol to give 7-chloro-[(5H-dibenzo[b,e][1,4]diazepin-11-yl)amino]-acetaldehyde dimethyl acetal.

Sources & evidence

ORD record
ord-e10d87593812415a83937657491eb3d4
Source dataset
uspto-grants-1976_05
Patent number
US03956297

Reaction notes

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