4-Chlorophenyl Isocyanate → HCID 131710199, compound

Participants

Reaction Steps

5.5 Parts of 7,14-diazadispiro[5.1.5.2]pentadecan-15-one, 3.84 parts of p-chlorophenyl isocyanate and a trace of 1,4-diazabicyclo[2.2.2]octane in 100 parts of dry benzene were heated at reflux for 36 hours. The solvent was removed in vacuo to yield a solid material which was recrystallised twice from petroleum ether of boiling range 60° to 80°C affording 5.6 parts of 14-p-chlorophenylcarbamoyl-7,14-diazadispiro[5.1.5.2]pentadecan-15-one as colourless needles of melting point 139° to 141°C. This material gave the following elemental analysis by weight:

Provenance & Evidence