Benzenesulfonyl chloride → HCID 13923715, compound

Participants

Reaction Steps

580 g. of monochlorobenzene were added to an aqueous solution of 116 g. (1 mole) of 2-chloroethylamine hydrochloride in 450 g. of water and 177 g. (1 mole) of benzenesulfonylchloride, and then the mixture was stirred at 10° ± 3°C. for 3 hours while adjusting pH to 6.5 to 8.5 with 138 g. (1 mole) of potassium carbonate. After completion of the reaction, the reaction solution was treated in the same manner as described in Example 3 to obtain 2-chloroethylbenzenesulfonamide in 94 % of yield.

Provenance & Evidence