Benzenesulfonyl chloride → HCID 13923715, compound

HRID 1076290Notes

Reaction equation

HRID 1076290 reaction equation
[Cl:1][C:2]1[CH:7]=CC=CC=1.Cl.ClCC[NH2:12].[C:13]1([S:19](Cl)(=[O:21])=[O:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.C(=O)([O-])[O-].[K+].[K+]>O>[Cl:1][CH2:2][CH2:7][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=1[S:19]([NH2:12])(=[O:21])=[O:20]

Participants

6

Reactant 4

HCID 7369Benzenesulfonyl chlorideHCID 7964ChlorobenzeneHCID 11430Potassium CarbonateHCID 97937372-Chloroethylamine hydrochloride

Product 1

HCID 13923715HCID 13923715, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

580 g. of monochlorobenzene were added to an aqueous solution of 116 g. (1 mole) of 2-chloroethylamine hydrochloride in 450 g. of water and 177 g. (1 mole) of benzenesulfonylchloride, and then the mixture was stirred at 10° ± 3°C. for 3 hours while adjusting pH to 6.5 to 8.5 with 138 g. (1 mole) of potassium carbonate. After completion of the reaction, the reaction solution was treated in the same manner as described in Example 3 to obtain 2-chloroethylbenzenesulfonamide in 94 % of yield.

Workup

  1. customAfter completion of the reaction
  2. additionthe reaction solution was treated in the same manner

Sources & evidence

ORD record
ord-5a7b50ef602c4a45b90e8aca5387c918
Source dataset
uspto-grants-1976_05
Patent number
US03956385

Reaction notes

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