4-Chlorobenzaldehyde → HCID 53690556, compound

HRID 1076320Notes

Reaction equation

HRID 1076320 reaction equation
[OH-].[Na+].[Cl:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1.[C:12]1([CH:18]([CH2:22][CH:23]=[CH:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:19](=[O:21])[CH3:20])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C(O)C>[Cl:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[CH:20][C:19](=[O:21])[CH:18]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:22][CH:23]=[CH:24][C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)=[CH:6][CH:5]=1

Participants

5

Reactant 3

HCID 77264-ChlorobenzaldehydeHCID 14798Sodium HydroxideHCID 53698084HCID 53698084, compound

Product 1

HCID 53690556HCID 53690556, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A sodium hydroxide solution (2.5 ml., 20%) is added to a solution of p-chlorobenzaldehyde (7.0 g., 0.05 mole) and 3,6-diphenyl-5-hexen-2-one (12.5 g., 0.05 mole) in ethanol (125 ml.) with stirring. The yellowish solid that separates on continued stirring is filtered, washed with cold ethanol, and air-dried, 14.35 g., m.p. 92°-95°C. Recrystallization from hexane gives material with m.p. 95°-96.5°C.

Workup

  1. stirringThe yellowish solid that separates on continued stirring
  2. filtrationis filtered
  3. washwashed with cold ethanol
  4. customair-dried
  5. customRecrystallization from hexane
  6. customgives material with m.p. 95°-96.5°C.

Sources & evidence

ORD record
ord-43cf824840bf47c9ab0ebdf0f9a77806
Source dataset
uspto-grants-1976_05
Patent number
US03956374

Reaction notes

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