Diethyl Ether → HCID 21539916, compound

HRID 1076348Notes

Reaction equation

HRID 1076348 reaction equation
[C:1]1(=[O:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7]C=2)[CH2:3][CH2:2]1.[CH3:11][S:12](Cl)(=[O:14])=[O:13].C(=O)([O-])[O-].[K+].[K+].CC[O:24][CH2:25][CH3:26]>CC(C)=O>[CH3:11][S:12]([O:10][C:1]1[CH:9]=[C:26]2[C:4]([CH2:5][CH:6]([CH3:7])[C:25]2=[O:24])=[CH:3][CH:2]=1)(=[O:14])=[O:13]

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 67351-IndanoneHCID 11430Potassium CarbonateHCID 31297Methanesulfonyl chloride

Product 1

HCID 21539916HCID 21539916, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of the indanone above (5.0 gm.), methanesulfonyl chloride (3.7 gm.) and potassium carbonate (5.0 gm.) in acetone (50 ml.) is refluxed for 24 hrs. Ether (100 ml.) is added and the ether layer washed with water (2 × 50 ml.), dried (MgSO4), filtered and evaporated to dryness to give the 6-methanesulfonyloxy-2-methylindanone (5.0 gm.) as a yellow oil.

Workup

  1. temperatureis refluxed for 24 hrs
  2. washthe ether layer washed with water (2 × 50 ml.)
  3. dry with materialdried (MgSO4)
  4. filtrationfiltered
  5. customevaporated to dryness

Sources & evidence

ORD record
ord-694201a77c904948ad541847f49e4ad1
Source dataset
uspto-grants-1976_05
Patent number
US03956363

Reaction notes

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