反应详情

12.92 g (40mmols) of Z-Thr(tBu)-OMe are hydrogenated in 200 ml of glacial acetic acid and 3 g of Pd-charcoal (10%) at room temperature. The hydrogen uptake is finished after 1 hour. The solution is freed of the catalyst by filtration and is evaporated in a waterpump vacuum at 35°C. After drying in a high vacuum at 35°C 7.3 g of an oil result, which according to a thin layer chromatogram is a single substance and is directly further used.

1. customat room temperature
2. filtrationThe solution is freed of the catalyst by filtration
3. customis evaporated in a waterpump vacuum at 35°C
4. dry with materialAfter drying in a high vacuum at 35°C 7.3 g of an oil
5. customresult