HuagongsheHuagongshe Chemistry Print Report · For research reference only
Z-Asn-Phe-NHNH-BOC → H-Asn-Phe-NH-NH-BOC
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Z-Asn-Phe-NHNH-BOC | HCID 131710203 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | H-Asn-Phe-NH-NH-BOC | HCID 131710205 | — |
Reaction Steps
28.75 g of the carbobenzoxy compound of 25, dissolved in 1 liter of methanol, are hydrogenated at room temperature in the presence of 2.9 g of 10 % strength palladium-charcoal. After complete decarbobenzoxylation the catalyst is filtered off and the filtrate is evaporated to dryness. The product melts at 160°- 161°C. Rf = 0.15 in chloroform-methanol (8:2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03956260 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-8da146caeb004e359130499d26ed541a |
| Source note | uspto-grants-1976_05 |