Gluconic Acid → delta-Gluconolactone

HRID 1076456Notes

Reaction equation

HRID 1076456 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].O=C(O)[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O>>[CH2:11]([OH:12])[C@H:9]1[O:10][C:2](=[O:1])[C@H:3]([OH:4])[C@@H:5]([OH:6])[C@@H:7]1[OH:8]

Participants

3

Reactant 2

HCID 10690Gluconic AcidHCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 7027delta-Gluconolactone

Procedure

The wet immobilized cells of Example 1 (47.3 g) were placed in 100 ml of an aqueous solution containing 10 g of glucose, and the mixture was stirred with aeration for 21 hours at room temperature. A 99% conversion to a mixture of gluconic acid and delta gluconolactone was obtained, and 75% of the original enzyme activity was recovered.

Sources & evidence

ORD record
ord-bdfc7c66097d406b99d5db241e3fd050
Source dataset
uspto-grants-1976_05
Patent number
US03957580

Reaction notes

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