HuagongsheHuagongshe Chemistry Print Report · For research reference only
2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo- → HCID 131710238, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo- | HCID 81242 | — |
| Reactant | HCID 21537306 | HCID 21537306 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 131710238 | HCID 131710238 | — |
Reaction Steps
In the manner given in Example 1, 3-amino-6-chloro-3,4-dihydro-4-hydroxy-4-(2,6-difluorophenyl)quinazoline with pyridine is reacted with α-phthalimidoacetyl chloride to give 1,3-dioxo-2-isoindolineacetic acid, [[N-[2-(2,6-difluorobenzoyl)-4-chlorophenyl]-1,3-dioxo-2-isoindolineacetamido]methylene]hydrazide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03957761 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-9ec11323c2bb4c149f7f2afa83c366f1 |
| Source note | uspto-grants-1976_05 |