Sodium Bicarbonate → 5-chloro-2-[3-[(dipropylamino)-methyl]-5-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]-benzophenone

HRID 1076627Notes

Reaction equation

HRID 1076627 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[CH:20]=[N:19][N:18]=[C:17]2[CH2:21][N:22]2[C:26](=[O:27])[C:25]3=[CH:28][CH:29]=[CH:30][CH:31]=[C:24]3[C:23]2=[O:32])=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8].C(=O)(O)[O-].[Na+]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:17]([CH2:21][N:22]3[C:26](=[O:27])[C:25]4=[CH:28][CH:29]=[CH:30][CH:31]=[C:24]4[C:23]3=[O:32])=[N:18][N:19]=[C:20]2[CH2:21][N:22]([CH2:26][CH2:25][CH3:28])[CH2:23][CH2:24][CH3:31])=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8]

Participants

3

Reactant 2

HCID 516892Sodium BicarbonateHCID 126119465-chloro-2-(3-phthalimidomethyl-4H-1,2,4-triazol-4-yl)benzophenone

Product 1

HCID 215372555-chloro-2-[3-[(dipropylamino)-methyl]-5-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]-benzophenone

Procedure

In the manner given in Example 13, 5-chloro-2-[3-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]benzophenone is reacted with the above suspension then neutralized with sodium bicarbonate to give 5-chloro-2-[3-[(dipropylamino)-methyl] -5-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]-benzophenone.

Workup

  1. customis reacted with the above suspension

Sources & evidence

ORD record
ord-34889cc7c4824ce095d785f15f67da7e
Source dataset
uspto-grants-1976_05
Patent number
US03957761

Reaction notes

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