Sodium Bicarbonate → 2'-chloro-5-nitro2-[3-(pyrrolidinomethyl)-5-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]benzophenone

HRID 1076628Notes

Reaction equation

HRID 1076628 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:35])[C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][C:10]=1[N:18]1[CH:22]=[N:21][N:20]=[C:19]1[CH2:23][N:24]1[C:28](=[O:29])[C:27]2=[CH:30][CH:31]=[CH:32][CH:33]=[C:26]2[C:25]1=[O:34].C(=O)(O)[O-].[Na+]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:35])[C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][C:10]=1[N:18]1[C:19]([CH2:23][N:24]2[C:25](=[O:34])[C:26]3=[CH:33][CH:32]=[CH:31][CH:30]=[C:27]3[C:28]2=[O:29])=[N:20][N:21]=[C:22]1[CH2:23][N:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 516892Sodium BicarbonateHCID 214988805-nitro-2-(3-phthalimidomethyl-4H-1,2,4-triazol-4-yl)-2'-chlorobenzophenone

Product 1

HCID 215372712'-chloro-5-nitro2-[3-(pyrrolidinomethyl)-5-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]benzophenone

Procedure

In the manner given in Example 13, 2'-chloro-5-nitro-2-[3-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]benzophenone is reacted with the above suspension then neutralized with sodium bicarbonate to give 2'-chloro-5-nitro-2[3-(pyrrolidinomethyl)-5-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]benzophenone.

Workup

  1. customis reacted with the above suspension

Sources & evidence

ORD record
ord-11e15e576a0846f88c07de66207f7eea
Source dataset
uspto-grants-1976_05
Patent number
US03957761

Reaction notes

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