HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → Benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 1H-1,4-Benzodiazepine | HCID 148431 | — |
| Reactant | HCID 21537264 | HCID 21537264 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Benzodiazepine | HCID 134664 | — |
Reaction Steps
In the manner [1,4]benzodiazepin. in Example 27, 2'-chloro-5-nitro2-[3-[(dimethylamino)methyl]-5-(phthalimidomethyl)-4H-1,2,4triazol-4-yl]benzophenone is heated in ethanol with hydrazine hydrate to give 8-nitro-1-[(dimethylamino)methyl] -6-(o-chlorophenyl)-4H-s-triazolo[4,3-a]1,4]benzodiazepin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03957761 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-b23d7f7f3b7c46969489a565b1e3d5b2 |
| Source note | uspto-grants-1976_05 |