HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Triethylamine → 1-(3,3-Diphenylpropyl)-4-(3,4,5-trimethoxybenzyl)piperazine dihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| Edukt | N-3,3-Diphenylpropylpiperazine | HCID 10356330 | — |
| Lösungsmittel | O-Xylene | HCID 7237 | — |
| Produkt | 1-(3,3-Diphenylpropyl)-4-(3,4,5-trimethoxybenzyl)piperazine dihydrochloride | HCID 21537822 | 76,7% |
Reaktionsschritte
N-3,3-Diphenylpropylpiperazine in the amount of 14.0 g (0.05 mole), 10.8 g (0.05 mole) of 3,4,5-trimethoxybenzylchloride, and 5.05 g (0.05 mole) of triethylamine were dissolved in 100 ml of xylene, and the same procedure as that of Example 1 was followed to obtain 20.4 g of 1-(3,3-diphenylpropyl)-4-(3,4,5-trimethoxybenzyl)piperazine dihydrochloride (76.7% yield) with a melting point of 178°C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US03957790 |
| Quelldatensatz | uspto-grants-1976_05 |
| ORD ID | ord-448561732c034efd8e722f9250aa7366 |
| Quellennotiz | uspto-grants-1976_05 |