1-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetralone → 6,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-One

HRID 1076810Notes

Reaction equation

HRID 1076810 reaction equation
C1C2C=C3C(=O)C(C=2C=CC=1)C=CC=C3.Cl[CH2:17][CH2:18][CH2:19][CH2:20][C:21]1([CH3:34])[C:30]2[C:25](=[CH:26][C:27]([O:31][CH3:32])=[CH:28][CH:29]=2)[CH2:24][CH2:23][C:22]1=[O:33]>>[CH3:32][O:31][C:27]1[CH:28]=[CH:29][C:30]2[C:21]3([CH3:34])[C:22](=[O:33])[CH:23]([CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:24][C:25]=2[CH:26]=1

Participants

3

Reactant 2

HCID 214100831-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetraloneHCID 1317102425,10-methano-5H-benzocyclononen-12-one

Product 1

HCID 214101276,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-One

Procedure

Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl)- 5,10-methano-5H-benzocyclononen-12-one, there is obtained from 30.5 g. of 1-(4-chlorobutyl)-1-methyl-6-methoxy-2-tetralone 15 g. of the title product, b.p. 140° to 145° C. (0.5 mm.).

Workup

  1. customthere is obtained from 30.5 g

Sources & evidence

ORD record
ord-9d2bd36c1f7b4481aedd7c086767a85b
Source dataset
uspto-grants-1976_05
Patent number
US03957872

Reaction notes

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