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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1076810Generated: November 4, 2026

1-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetralone → 6,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-One

https://huagongshe.com/reaction/1076810

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chlorobutyl)-1-methyl-6-methoxy-2-tetraloneHCID 21410083—
Reactant5,10-methano-5H-benzocyclononen-12-oneHCID 131710242—
Product6,7,8,9,10,11-Hexahydro-2-Methoxy-5Methyl-5,10-Methano-5H-Benzocyclononen-12-OneHCID 21410127—

Reaction Steps

Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl)- 5,10-methano-5H-benzocyclononen-12-one, there is obtained from 30.5 g. of 1-(4-chlorobutyl)-1-methyl-6-methoxy-2-tetralone 15 g. of the title product, b.p. 140° to 145° C. (0.5 mm.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03957872
Source datasetuspto-grants-1976_05
ORD IDord-9d2bd36c1f7b4481aedd7c086767a85b
Source noteuspto-grants-1976_05