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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1076879Generated: November 1, 2026

2-(6-Methoxy-2-naphthyl)propionic acid → 2-(6-Methoxynaphthalen-2-yl)propan-1-ol

https://huagongshe.com/reaction/1076879

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-Methoxy-2-naphthyl)propionic acidHCID 1302—
ReactantDiethyl EtherHCID 3283—
ReactantEthyl AcetateHCID 8857—
ReactantAluminium lithium hydrideHCID 21226445—
SolventWaterHCID 962—
Product2-(6-Methoxynaphthalen-2-yl)propan-1-olHCID 33341—

Reaction Conditions

Temperature0 °C

Reaction Steps

To a mixture of 0.4 g. of lithium aluminum hydride and 100 ml. of ethyl ether, there is added a mixture of 2.3 g. of d 2-(6-methoxy-2-naphthyl)propionic acid and 100 ml. of ethyl ether. The mixture is stirred at 0°C for 30 minutes, and 10 ml. of ethyl acetate is added. After 1 hour, 4 ml. of water is added to the mixture. The resulting mixture is filtered and evaporated under reduced pressure to yield l 2-(6-methoxy-2-naphthyl)-l-propanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03958012
Source datasetuspto-grants-1976_05
ORD IDord-b381236aa1e845b3ab93dac1c1593394
Source noteuspto-grants-1976_05