10-Chloro-1,4,6,9-tetrahydro-4,6-dioxopyrido(3,2-g)quinoline-2,8-dicarboxylic acid → HCID 22759120, compound

HRID 1076983Notes

Reaction equation

HRID 1076983 reaction equation
[Cl:1][C:2]1[C:3]2[NH:19][C:18]([C:20]([OH:22])=[O:21])=[CH:17][C:16](=[O:23])[C:4]=2[CH:5]=[C:6]2[C:11]=1[NH:10][C:9]([C:12]([OH:14])=[O:13])=[CH:8][C:7]2=[O:15].C(=O)(O)[O-].[Na+:28]>>[Cl:1][C:2]1[C:11]2[NH:10][C:9]([C:12]([O-:14])=[O:13])=[CH:8][C:7](=[O:15])[C:6]=2[CH:5]=[C:4]2[C:3]=1[NH:19][C:18]([C:20]([O-:22])=[O:21])=[CH:17][C:16]2=[O:23].[Na+:28].[Na+:28]

Participants

3

Reactant 2

HCID 7277510-Chloro-1,4,6,9-tetrahydro-4,6-dioxopyrido(3,2-g)quinoline-2,8-dicarboxylic acidHCID 516892Sodium Bicarbonate

Product 1

HCID 22759120HCID 22759120, compound

Procedure

The diacid prepared in Example 7 is dissolved in hot 4% sodium bicarbonate. Upon cooling, the disodium salt precipitates and is collected by filtration. Recrystallization from water gives a yellow solid melting above 310° C.

Workup

  1. temperatureUpon cooling
  2. customthe disodium salt precipitates
  3. filtrationis collected by filtration
  4. customRecrystallization from water
  5. customgives a yellow solid
  6. custommelting above 310° C.

Sources & evidence

ORD record
ord-cc3665ea6f974a40982388fd23896fe2
Source dataset
uspto-grants-1976_05
Patent number
US03959289

Reaction notes

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