Sodium Hydroxide → HCID 54502363, compound

HRID 1077069Notes

Reaction equation

HRID 1077069 reaction equation
S(O)(O)(=O)=O.[CH3:6][S:7][C:8](=[NH:10])[NH2:9].Cl[C:12]([O:14][CH3:15])=[S:13].[OH-].[Na+]>O>[NH2:10][C:8](=[N:9][C:12](=[S:13])[O:14][CH3:15])[S:7][CH3:6]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 752702-Methyl-2-thiopseudourea sulfateHCID 554404Methyl chloromethanethioate

Product 1

HCID 54502363HCID 54502363, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 69.5 parts 2-methyl-2-thiopseudourea sulfate and 110 parts methyl chlorothioformate in 500 ml. of water is added dropwise at 0°-5°C. 120 parts 50% sodium hydroxide. The reaction mixture is stirred at 0°-5°C. for 1 hour and then at room temperature for 2 hours. The solution is extracted with methylene chloride. The methylene chloride extract is then dried and the solvent evaporated on a rotary evaporator to give 47 parts of methyl N-(1-amino-1-methylthiomethylene)thiocarbamate melting at 75°-76°C.

Workup

  1. waitat room temperature for 2 hours
  2. extractionThe solution is extracted with methylene chloride
  3. extractionThe methylene chloride extract
  4. customis then dried
  5. customthe solvent evaporated on a rotary evaporator

Sources & evidence

ORD record
ord-afda05c4c57e4b31a0752e90a11d170c
Source dataset
uspto-grants-1976_05
Patent number
US03959331

Reaction notes

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