Tetrahydrofuran → 4-(3-Hydroxy-2-methylpropyl)-1,4-benzoxazin-3-one

HRID 107708Notes

Reaction equation

HRID 107708 reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][CH:8]([CH2:9][N:10]1[C:11](=[O:20])[CH2:12][O:13][c:14]2[c:15]1[cH:16][cH:17][cH:18][cH:19]2)[CH3:21])([CH3:5])([CH3:22])[CH3:23].[CH2:25]([N+:26]([CH2:27][CH2:28][CH2:29][CH3:30])([CH2:31][CH2:32][CH2:33][CH3:34])[CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH3:41].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[F-:24]>>[OH:6][CH2:7][CH:8]([CH2:9][N:10]1[C:11](=[O:20])[CH2:12][O:13][c:14]2[c:15]1[cH:16][cH:17][cH:18][cH:19]2)[CH3:21]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 689101304-[3-(tert-Butyldimethylsilanyloxy)-2-methylpropyl]-4H-benzo[1,4]oxazin-3-one

Product 1

HCID 689112424-(3-Hydroxy-2-methylpropyl)-1,4-benzoxazin-3-one

Sources & evidence

ORD record
ord-25c30b2454d1412e97bdfdb257bf5a1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…