2-Fluorophenol → HCID 21535986, compound

HRID 1077087Notes

Reaction equation

HRID 1077087 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].Br[C:10]1[CH:15]=[CH:14][C:13]([Br:16])=[CH:12][C:11]=1[N+:17]([O-:19])=[O:18]>>[Br:16][C:13]1[CH:14]=[CH:15][C:10]([O:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])=[C:11]([N+:17]([O-:19])=[O:18])[CH:12]=1

Participants

3

Reactant 2

HCID 97072-FluorophenolHCID 770041,4-Dibromo-2-nitrobenzene

Product 1

HCID 21535986HCID 21535986, compound

Procedure

2-Fluorophenol and 2,5-dibromo-1-nitrobenzene were reacted together under Ullmann conditions to give 1-bromo-4-(2-fluorophenoxy)-3-nitrobenzene which was reduced and deaminated to give the desired product b.p. 112°-116°C./0.8mm.

Sources & evidence

ORD record
ord-2f10bef387ff406b83719e2f058bf194
Source dataset
uspto-grants-1976_05
Patent number
US03959364

Reaction notes

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