反应详情

Add mercuric sulphate (0.45 g) to a stirred solution of 1-diethylamino-6-(3,4-dimethoxyphenyl)hex-2-yne (8.5 g) in concentrated sulphuric acid (2.5 cc) and water (25 cc) and maintain the solution at 75° for 90 minutes. Make the cooled solution basic with 10% aqueous sodium hydroxide and filter to remove mercuric oxide. Extract the product with ether and wash and dry the ethereal solution. Evaporate the solvent to obtain 1-diethylamino-6-(3,4-dimethoxyphenyl)hexan-3-one as an oily residue.

1. temperaturemaintain the solution at 75° for 90 minutes
2. filtrationfilter
3. customto remove mercuric oxide
4. extractionExtract the product with ether
5. washwash
6. customdry the ethereal solution
7. customEvaporate the solvent