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Sodium Hydroxide → 1-Diethylamino-6-(3,4-dimethoxyphenyl)hexan-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 1-Diethylamino-6-(3,4-dimethoxyphenyl)hex-2-yne | HCID 21485725 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | 1-Diethylamino-6-(3,4-dimethoxyphenyl)hexan-3-one | HCID 21485415 | — |
反応手順
Add mercuric sulphate (0.45 g) to a stirred solution of 1-diethylamino-6-(3,4-dimethoxyphenyl)hex-2-yne (8.5 g) in concentrated sulphuric acid (2.5 cc) and water (25 cc) and maintain the solution at 75° for 90 minutes. Make the cooled solution basic with 10% aqueous sodium hydroxide and filter to remove mercuric oxide. Extract the product with ether and wash and dry the ethereal solution. Evaporate the solvent to obtain 1-diethylamino-6-(3,4-dimethoxyphenyl)hexan-3-one as an oily residue.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03959322 |
| 出典データセット | uspto-grants-1976_05 |
| ORD ID | ord-3b2d3fd4a2a4469799fd00f7177213a0 |
| 出典メモ | uspto-grants-1976_05 |