Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-1,3-cyclopentanedione → 2-(6-m-Methoxyphenyl-3-oxohexyl)-2-methylcyclopentane-1,3-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-1,3-cyclopentanedione | HCID 13005 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | 1-Bromo-6-(m-methoxyphenyl)hexan-3-one | HCID 21485513 | — |
| 생성물 | 2-(6-m-Methoxyphenyl-3-oxohexyl)-2-methylcyclopentane-1,3-dione | HCID 20350002 | — |
반응 단계
Add sodium (0.05 g) to a 0.12% methanolic potassium hydroxide solution (15 cc). To this solution add 1-bromo-6-(m-methoxyphenyl)hexan-3-one (0.9 g) in methaol (5 cc) and 2-methylcyclopentane-1,3-dione (0.4 g), and reflux the mixture for 6 hours. After working up as in the preparation of the title compound in a previous example, obtain the crude Michael adduct 2-(6-m-methoxyphenyl-3-oxohexyl)-2-methylcyclopentane-1,3-dione as a yellow gum.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03959322 |
| 출처 데이터셋 | uspto-grants-1976_05 |
| ORD ID | ord-c30c62c5a72a467f8c4f2e0bee97c2cc |
| 출처 메모 | uspto-grants-1976_05 |