化工社化工社 化学情報印刷レポート · 研究参考用
3-Cyclopentylpropionyl chloride → 13beta-Ethyl-17beta-(3-cyclopentylpropionoxy)-gon-4-en-3-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Cyclopentylpropionyl chloride | HCID 66039 | — |
| 反応物 | Gon-4-en-3-one, 13-ethyl-17-hydroxy-, (17beta)-(+-)- | HCID 10039774 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 13beta-Ethyl-17beta-(3-cyclopentylpropionoxy)-gon-4-en-3-one | HCID 22790393 | — |
反応手順
Add 3-cyclopentylpropionyl chloride (2 g.) in benzene (6 cc.) to 13β-ethyl-17β-hydroxy-gon-4-en-3-one (2 g.) in pyridine (6 cc.) at -15°. Keep the mixture at -10° for 17 hours, work up and recrystallize the product from methanol to give the title compound, m.p. 88-89°; ultraviolet absorption peak at 241 mμ (ε17,000); infrared absorption peaks at 5.80; 6.00, 6.18 μ.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03959322 |
| 出典データセット | uspto-grants-1976_05 |
| ORD ID | ord-96165fb019b74be28d1fca38a215fd69 |
| 出典メモ | uspto-grants-1976_05 |