HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 178426530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Sodium Bisulfite | HCID 23665763 | — |
| Reactant | HCID 178426531 | HCID 178426531 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178426530 | HCID 178426530 | — |
Reaction Steps
To a slurry of 10 g. (0.0523 mole) of 1-(p-tolyl)biguanide in 175 ml of water is added dropwise 8.4 g. (0.053 mole) of bromine over a period of 3 hours. The reaction mixture is cooled and the unreacted bromine discharged with sodium bisulfite. The mixture is made strongly alkaline and extracted into ether. The ether layer is dried over Na2SO4, charcoaled, filtered and evaporated to obtain 1-(2-bromo-4-methylphenyl)biguanide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03959488 |
| Source dataset | uspto-grants-1976_05 |
| ORD ID | ord-307dc130910d46ea944e8cd9d5e1f9c8 |
| Source note | uspto-grants-1976_05 |