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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1077376Generated: October 31, 2026

n-(3-chloro-4-nitrophenyl)acetamide → 2-Ethylthio-4-Acetylaminonitrobenzene

https://huagongshe.com/reaction/1077376

Reaction equation

Participants

RoleNameHCIDCharge
Reactantn-(3-chloro-4-nitrophenyl)acetamideHCID 236820—
ReactantSodium ethanethiolateHCID 4459711—
Solvent1,2-DimethoxyethaneHCID 8071—
Product2-Ethylthio-4-AcetylaminonitrobenzeneHCID 19431135—

Reaction Steps

To a suspension of 25.2 g (0.3 mol) of sodium thioethoxide in 220 ml of dimethoxyethane at room temperature are added, portionwise over 30 minutes with stirring, 46.2 g (0.216 mol) of 2-chloro-4-acetylaminonitrobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05542952
Source datasetuspto-grants-1996_08
ORD IDord-6945b1e15ae84d1fbc06cbdf82481a3e
Source noteuspto-grants-1996_08