HCID 19431302, compound → HCID 19431320, compound

HRID 1077403Notes

Reaction equation

HRID 1077403 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[CH2:8][CH:7]=[C:6]2[C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1.[H][H]>C(O)C.[Pd]>[CH3:13][O:12][C:11]1[CH:10]=[C:9]2[C:5](=[CH:4][C:3]=1[O:2][CH3:1])[CH:6]([C:14]1[CH:15]=[CH:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=1)[CH2:7][CH2:8]2

Participants

5

Reactant 2

HCID 19431302HCID 19431302, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 19431320HCID 19431320, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 5,6-dimethoxy-3-(4-methoxyphenyl)indene (1.5 g, 5.32 mmol) in 60 ml of ethanol is hydrogenated in an autoclave in the presence of palladium on carbon (10%, 25 mg) under 5 bars of hydrogen for 1.5 h. After filtration of the catalyst, the evaporation of the solvent gives an oil which gradually solidifies (1.5 g, 100%).

Workup

  1. filtrationAfter filtration of the catalyst
  2. customthe evaporation of the solvent
  3. customgives an oil which

Sources & evidence

ORD record
ord-e48a5b729d5640b395a7660d964690e0
Source dataset
uspto-grants-1996_08
Patent number
US05543298

Reaction notes

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