HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54029226, compound → HCID 19431958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54029226 | HCID 54029226 | — |
| Reactant | 3-(1,1,2,2-Tetrafluoroethoxy)phenylguanidine nitrate | HCID 178512518 | — |
| Product | HCID 19431958 | HCID 19431958 | — |
Reaction Steps
In accordance with the general procedure described in Example 1, reaction of 226.2 mg (1.0 mmol) of 3-dimethylamino-(4-isoquinolyl)-2-propen-1-one and 185 g (0.60 mmol) of 3-(1,1,2,2-tetrafluoroethoxy)phenylguanidine nitrate gives N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-4-(4-isoquinolyl)-2-pyrimidine-amine; FAB-MS:415 (M+ +1), m.p. 158°-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05543520 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-2657ec1bace84052878c9e8b9e7a2f1b |
| Source note | uspto-grants-1996_08 |