Hydrazine hydrate (1:1) → HCID 19431918, compound

HRID 1077563Notes

Reaction equation

HRID 1077563 reaction equation
C([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[NH:10][C:11]3[C:16]([C:17]=2[C:18]=1[CH2:19][O:20][CH3:21])=[C:15]([O:22][CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[CH:14]=[CH:13][CH:12]=3)=O)C.O.[NH2:31][NH2:32]>>[CH2:23]([O:22][C:15]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:16]=1[C:17]1[C:18]([CH2:19][O:20][CH3:21])=[C:6]([C:4]([NH:31][NH2:32])=[O:3])[N:7]=[CH:8][C:9]=1[NH:10]2)[C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 123700ZK 91296

Product 1

HCID 19431918HCID 19431918, compound

Procedure

1.56 g of 5-benzyloxy-4-methoxymethyl-β-carboline-3-carboxylic acid-ethyl ester is refluxed in 20 ml of hydrazine hydrate (80%) for 4 hours. After cooling, the precipitated crystals are suctioned off and dried. 1.2 g of 5-benzyloxy-4-methoxymethyl-β-carboline-3-carboxylic acid-hydrazide of a melting point of 212°-213° C. is obtained.

Workup

  1. temperatureAfter cooling
  2. customdried

Sources & evidence

ORD record
ord-dc9575bc87684b668b5b3befe5482ba9
Source dataset
uspto-grants-1996_08
Patent number
US05543519

Reaction notes

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