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HRID1077915

反应详情

EQUATION

反应方程式

HRID 1077915 的结构方程式

REACTANTS

反应物

3
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：CC(C)(C)OC(=O)COC1CCNCC1
HCID10036224

tert-butyl (piperidin-4-yloxy)-acetate

C11H21NO3

结构：C[C@@]1(C(=O)O)CCCN1C(=O)c1ccc(C#N)cc1
HCID10445222

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)COC1CCN(C(=O)[C@]2(C)CCCN2C(=O)c2ccc(C#N)cc2)CC1
HCID10321793

未命名化合物

PROCEDURE

实验过程

By reacting 1.67 g of t-butyl 4-piperidinyloxyacetate with 0.8 g of the acid chloride of 1-(p-cyanobenzoyl)-2-methyl-L-proline (obtained by treating the product of the previous step with thionyl chloride) there is obtained 0.89 g of t-butyl [[1-[1-(p-cyanobenzoyl)-2-methyl-L-prolyl]-4-piperidinyl]oxy]acetate. M.p. 180°-182° C. (ethyl acetate).

WORKUP

后处理

  1. customobtained