HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 10321793, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Tert-butyl (piperidin-4-yloxy)-acetate | HCID 10036224 | — |
| Reactant | HCID 10445222 | HCID 10445222 | — |
| Product | HCID 10321793 | HCID 10321793 | — |
Reaction Steps
By reacting 1.67 g of t-butyl 4-piperidinyloxyacetate with 0.8 g of the acid chloride of 1-(p-cyanobenzoyl)-2-methyl-L-proline (obtained by treating the product of the previous step with thionyl chloride) there is obtained 0.89 g of t-butyl [[1-[1-(p-cyanobenzoyl)-2-methyl-L-prolyl]-4-piperidinyl]oxy]acetate. M.p. 180°-182° C. (ethyl acetate).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05545658 |
| Source dataset | uspto-grants-1996_08 |
| ORD ID | ord-a3d61816c6d64ed4bf723cb4ec77ae79 |
| Source note | uspto-grants-1996_08 |