Pyridine → Tetralin

HRID 1078055Notes

Reaction equation

HRID 1078055 reaction equation
FC(F)(F)S(OS(C(F)(F)F)(=O)=O)(=O)=O.C(Cl)Cl.N1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:20]1[C:24]2[C:24](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:23][CH2:22][CH2:21]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 6344DichloromethaneHCID 67749Trifluoromethanesulfonic anhydride

Product 1

HCID 8404Tetralin

Procedure

In Step 3, A-3 is reacted with trifluoromethanesulfonic anhydride in the presence of methylene chloride and pyridine to provide A-4 tetralin.

Sources & evidence

ORD record
ord-3ece25dcc2b743a7b7c3a506c8cf2127
Source dataset
uspto-grants-1996_08
Patent number
US05545755

Reaction notes

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