Methanol → HCID 12548239, compound

HRID 1078094Notes

Reaction equation

HRID 1078094 reaction equation
O.O.O.O.O.O.O.O.O.[S-2:10].[Na+].[Na+].Br[CH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.CO>O1CCCC1>[C:16]1([CH2:15][CH2:14][S:10][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 7666Phenethyl bromideHCID 73972Sodium sulfide nonahydrate

Product 1

HCID 12548239HCID 12548239, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A solution of 7.65 g (32 mmol) of sodium sulfide nonahydrate and 8.7 ml (64 mmol) of 2-bromoethylbenzene in 150 ml of 1:1 tetrahydrofuran:methanol was heated at reflux under inert atmosphere. After 24 h, the solution was allowed to cool and concentrated in vacuo to give the crude desired compound.

Workup

  1. temperatureat reflux under inert atmosphere
  2. temperatureto cool
  3. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-7ade240fbad14c4dab80d53aa3fe40a9
Source dataset
uspto-grants-1996_08
Patent number
US05545750

Reaction notes

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